The Indian Institute of Chemical Biology (IICB) under the CSIR had shown in 2018 that the cells of the immune system may also be critically dependent on these channels to sense physical cues.
Back home, a group of IICB scientists led by immunologist Dipyaman Ganguly first showed in 2018 that the cells of the immune system may be critically dependent on these channels for sensing physical cues inside the body.
Their paper titled “Cutting Edge: Piezo1 Mechanosensors Optimize Human T Cell Activation”, published in The Journal of Immunology, provided the first evidence for the involvement of Piezo mechanosensors in immune regulation.